1-(4-Methoxyphenyl)pyrrolidine-2,5-dione
نویسندگان
چکیده
In the title compound, C11H11NO3, the di-hydro-furan-2,5-dione ring has a shallow envelope conformation, with one of the methyl-ene C atoms displaced by 0.216 (1) Å from the other atoms. These near-planar atoms subtend a dihedral angle of 55.88 (8)° with the benzene ring. In the crystal, C-H⋯O hydrogen bonds link the mol-ecules into [010] chains.
منابع مشابه
Anticonvulsant properties of N-(4-methylpiperazin-1-yl)- and N-[3-(4-methyl-piperazin-1-yl)propyl] derivatives of 3-aryl- and 3-spirocycloalkyl-pyrrolidine-2,5-dione.
Two series of N-(4-methylpiperazin-1-yl)- and N-[3-(4-methylpiperazin-1-yl)-propyl]-3-aryl- and 3-spirocycloalkyl-pyrrolidine-2,5-dione derivatives were synthesized and tested for anticonvulsant activity in the maximum electroshock (MES) seizure and pentetrazole (sc PTZ) seizure threshold tests. Compounds with an aromatic ring at position-3 of pyrrolidine-2,5-dione exhibited anticonvulsant acti...
متن کامل1-[2-(3-Methoxyphenyl)ethyl]pyrrolidine-2,5-dione
In the title compound, C13H15NO3, the pyrrolidine ring makes a dihedral angle of 4.69 (9)° with the 3-meth-oxy-phenyl ring. In the crystal, hydrogen-bonded chains running along [101] are generated by connecting neighbouring mol-ecules via C-H⋯O hydrogen bonds. Parallel chains are linked by further C-H⋯O hydrogen bonds, forming a three-dimensional structure.
متن کاملN-(7-Dibromomethyl-5-methyl-1,8-naphthyridin-2-yl)acetamide–pyrrolidine-2,5-dione (1/1)
In the title co-crystal, C(12)H(11)Br(2)N(3)O·C(4)H(5)NO(2), the naphthyridine derivative and the pyrrolidine-2,5-dione mol-ecules have crystallographic mirror-plane symmetry with all non-H atoms, except the Br atom, located on the mirror plane. In the crystal, N-H⋯N, N-H⋯O and C-H⋯O hydrogen bonds link the mol-ecules into heterodimers. These dimers are further linked into a one-dimensional str...
متن کاملAnti-inflammatory activities of new succinic and maleic derivatives from the fruiting body of Antrodia camphorata.
Six new compounds, trans-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]pyrrolidine-2,5-dione (1), trans-1-hydroxy-3-(4-hydroxyphenyl)-4-isobutylpyrrolidine-2,5-dione (2), cis-3-(4-hydroxyphenyl)-4-isobutyldihydrofuran-2,5-dione (3), 3-(4-hydroxyphenyl)-4-isobutyl-1H-pyrrole-2,5-dione (4), 3-(4-hydroxyphenyl)-4-isobutylfuran-2,5-dione (5), and dimethyl 2-(4-hydroxyphenyl)-3-isobutylmaleate (6), ...
متن کاملSynthesis and anticonvulsant properties of new 1-(2-pyridinyl)- 3-substituted pyrrolidine-2,5-dione derivatives.
The synthesis and anticonvulsant properties of new 1-(2-pyridinyl)- succinimides [I-XXII] differently substituted at the position-3 of imide ring have been described. The profile of pharmacological activity of these compounds was examined by a maximal electroshock (MES) and pentylenetetrazole (scPTZ) tests, whereas their neurotoxicity was determined using a rotarod screen. The results obtained ...
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عنوان ژورنال:
دوره 69 شماره
صفحات -
تاریخ انتشار 2013